The Polytechnic University of the Philippines, Manila (commonly known as PUP Main or PUP Santa Mesa) (Filipino: Politeknikong Unibersidad ng Pilipinas sa Maynila) is the flagship and the most prestigious member of the Polytechnic University of the Philippines System. It consists of three constituent campuses and is located in Santa Mesa, Manila.
The offices of the University Officials, Ninoy Aquino Learning Resources Center, and PUP Gym and open courts are located here. It has several campuses; the A. Mabini Campus that houses many of its colleges; MH del Pilar Campus that houses the College of Nutrition and Food Sciences and the College of Tourism, Hotel and Restaurant Management; NDC Campus that houses the College of Communication, the College of Engineering, College of Architecture and Fine Arts, The University Press and the Mass Communication Theatre.
PUP Manila is considered as one of the premier state universities in the country and excels in the disciplines of engineering, accountancy, computer science, communication, and social sciences. Entry to this PUP Main Campus is the most competitive and applicants must pass the Polytechnic University of the Philippines College Entrance Test.