España is an east-west artery of Manila. It connects Lerma and Nicanor Reyes (formerly Morayta) streets of Sampaloc district on the west end to Mabuhay (formerly Welcome) Rotonda, Quezon City on the east end. The entire street is straddled by a center island, which is only broken on major intersections and at the railroad crossing. Vehicles are not allowed to make a left-turn at the full length of the boulevard, with the exception of the intersection going to Nicanor Reyes Street at the western terminus. España is two kilometers long.
España's north side is its west-bound (Manila-bound) side, while the south side is its east-bound (Quezon City-bound) side. Buses, taxis, jeepneys and cabriolets serve the commuters.